Browse or Brush? An Exploration of Citizen-Government Interaction in the Municipal Realm

To gain a better understanding about new forms of citizen-government interaction enabled by modern technology, we conducted a survey among citizens who interact with their local government by using a web-based platform or a mobile application. In our paper, we investigate the patterns of online and mobile communication between citizens and local government. Based on logistic regressions, we study who possesses the characteristics that predict communication via web and mobile application. Empirical findings indicate that socio-demographic factors (gender, age, education) predict individuals’ usage of web over mobile devices. Those with experience in communicating with local government via traditional channels prefer the web interface to get in touch, whereas frequent communicators are more likely to use mobile phone

Shedding Light on Participation in Open Government Arenas: Determinants of Platform Activity of Web and App Users

This article develops and tests a model to explain web-based and mobile devices usage by citizens to interact with their local government. By employing literature from diverse fields of information systems research, the authors derive an integrated model that investigates citizen participation on a city improvement platform. The model proposes three overall influences on platform activity: technological influences (perceived ease of use, perceived usefulness), motivational influences (intrinsic motivation and prosocial motivation), and socio-demographic influences (gender, age, education), and is tested among two groups of users (i.e. web page and mobile app users). Empirical results show that platform activity of both web and mobile users is mainly driven by intrinsic and prosocial motivation. Whereas perceived usefulness is positively associated with platform behavior of web users, TAM variables have not effect on mobile users’ activity. While gender and age play a role regarding web activity, age and education influence mobile participation

Government Openness and Public Trust: The Mediating Role of Democratic Capacity

The open government paradigm implies public processes are becoming more transparent, public information is available online, and citizens and non‐governmental organizations are encouraged to interact with public administration through new platform‐based forms of participation and collaboration. Though these governmental efforts to open up organizational procedures to the public are meant to strengthen the relationship between citizens and the government, empirical evidence is currently sparse and mixed. This article argues that positive impacts of openness depend on citizens' democratic capacity defined as individual sense of empowerment to influence governmental systems. By matching individual survey data from the European Social Survey with secondary institutional data the authors investigate the relationship between individual and structural level variables. Findings indicate that structural openness is, in general, positively associated with higher trust. Further, the effect of openness on public trust is partially mediated by an individual's perception that they have meaningful opportunities for political participation

BENKLER REVISITED – VENTURING BEYOND THE OPEN SOURCE SOFTWARE ARENA?

The organizational principles of open source software (OSS) development have challenged traditional theories in economics, organization research and information systems. In a seminal paper, Benkler (2002) provided a comprehensive framework to structure and explain these OSS principles. Coined Commons-Based Peer Production (CBPP), his framework has inspired a large stream of research on OSS. The objective of our paper is to determine whether CBPP also provides a viable framework to investigate projects of open innovation in non-software related domains. Using a case study approach, we focus on four projects that attempt to operate in line with the OSS phenomenon, but deal with tangible outputs (biotechnology, automobiles, entertainment hardware, and public patent review). We show that in general the CBPP framework is well-suited to explain open value creation in these domains. However, we also find several factors which limit its adoption to non-software related arenas

Trajectories of local open government: An empirical investigation of managerial and political perceptions

‘Open government’ refers to transparent, participative decision-making and platform-based citizen-government collaboration and has emerged as one paradigm at the local government level, in particular. However, substantial disparities exist in open government adoption among municipalities, and the empirical evidence on the determinants of open government adoption is sparse and mixed. This article considers open government adoption by integrating the resource- and knowledge-based views and decision-makers’ open government willingness. We argue that the positive impacts of internal capacity depend on the municipal decision-makers’ open government willingness. Using data from a survey conducted among local decision-makers, we investigate organizational ability to implement open government and decision-makers' preferences and adoption level. The findings indicate that organizational capacity is positively associated with open government. In addition, the effect of ability on adoption is partially mediated by leaders’ perceptions that open government is a meaningful opportunity for the municipality

Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic Cultivation

Binder D, Probst C, Grünberger A, et al. Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic Cultivation. PLoS one. 2016;11(8): e0160711.Recombinant protein production is mostly realized with large-scale cultivations and monitored at the level of the entire population. Detailed knowledge of cell-to-cell variations with respect to cellular growth and product formation is limited, even though phenotypic heterogeneity may distinctly hamper overall production yields, especially for toxic or difficult-to-express proteins. Unraveling phenotypic heterogeneity is thus a key aspect in understanding and optimizing recombinant protein production in biotechnology and synthetic biology. Here, microfluidic single-cell analysis serves as the method of choice to investigate and unmask population heterogeneities in a dynamic and spatiotemporal fashion. In this study, we report on comparative microfluidic single-cell analyses of commonly used E. coli expression systems to uncover system-inherent specifications in the synthetic M9CA growth medium. To this end, the PT7lac/LacI, the PBAD/AraC and the Pm/XylS system were systematically analyzed in order to gain detailed insights into variations of growth behavior and expression phenotypes and thus to uncover individual strengths and deficiencies at the single-cell level. Specifically, we evaluated the impact of different system-specific inducers, inducer concentrations as well as genetic modifications that affect inducer-uptake and regulation of target gene expression on responsiveness and phenotypic heterogeneity. Interestingly, the most frequently applied expression system based on E. coli strain BL21(DE3) clearly fell behind with respect to expression homogeneity and robustness of growth. Moreover, both the choice of inducer and the presence of inducer uptake systems proved crucial for phenotypic heterogeneity. Conclusively, microfluidic evaluation of different inducible E. coli expression systems and setups identified the modified lacY-deficient PT7lac/LacI as well as the Pm/XylS system with conventional m-toluic acid induction as key players for precise and robust triggering of bacterial gene expression in E. coli in a homogeneous fashion

O-GlcNAcase:promiscuous hexosaminidase or key regulator of O-GlcNAc signalling?

O-GlcNAc signaling is regulated by an opposing pair of enzymes: O-GlcNAc transferase installs and O-GlcNAcase (OGA) removes the modification from proteins. The dynamics and regulation of this process are only beginning to be understood as the physiological functions of both enzymes are being probed using genetic and pharmacological approaches. This minireview charts the discovery and functional and structural analysis of OGA and summarizes the insights gained from recent studies using OGA inhibition, gene knock-out, and overexpression. We identify several areas of “known unknowns” that would benefit from future research, such as the enigmatic C-terminal domain of OGA

The open innovation research landscape: established perspectives and emerging themes across different levels of analysis

This paper provides an overview of the main perspectives and themes emerging in research on open innovation (OI). The paper is the result of a collaborative process among several OI scholars – having a common basis in the recurrent Professional Development Workshop on ‘Researching Open Innovation’ at the Annual Meeting of the Academy of Management. In this paper, we present opportunities for future research on OI, organised at different levels of analysis. We discuss some of the contingencies at these different levels, and argue that future research needs to study OI – originally an organisational-level phenomenon – across multiple levels of analysis. While our integrative framework allows comparing, contrasting and integrating various perspectives at different levels of analysis, further theorising will be needed to advance OI research. On this basis, we propose some new research categories as well as questions for future research – particularly those that span across research domains that have so far developed in isolation

Open innovation in public management: analysis of the Brazilian action plan for Open Government Partnership

Este estudo objetivou analisar o Plano de Ação brasileiro para o Governo Aberto, baseado na teoria da inovação aberta na gestão pública. Utilizou-se de uma pesquisa documental, com vistas a aprofundar o conhecimento do fenômeno em questão. O documento foi escolhido intencionalmente, por ser exemplo basilar das políticas públicas relacionadas à inovação aberta brasileira. Os resultados mostram que os compromissos firmados pelo governo brasileiro estão consoantes com o processo de inovação aberta pública. As ações previstas no Plano estão especificamente relacionadas a transparência, abertura de dados e preparação do corpo estatal para o processo aberto de inovação. _________________________________________________________________________________________ RESUMEN: Este estudio tuvo como objetivo analizar el Plan de Acción de Brasil para el Gobierno Abierto con base en la teoría de la innovación abierta en la gestión pública. Se utilizó una investigación documental, con el fin de profundizar el conocimiento en el fenómeno en cuestión. El documento fue elegido intencionadamente porque es fundamental para las políticas públicas relacionadas con la innovación abierta brasileña. Los resultados muestran que los compromisos asumidos por el gobierno brasileño son compatibles con el proceso de innovación abierta pública. En concreto, las acciones contenidas en el plan están relacionados con la transparencia, los datos abiertos y preparación de la estructura de gobierno para el proceso abierto de innovación. _________________________________________________________________________________________ ABSTRACT: This study aims to analyze the Brazilian action plan for Open Government, based on the theory of open innovation in public management. Documentary research was used, in order to deepen of the knowledge the phenomenon being discussed . The document was intentionally chosen because it is essential for public policies related to Brazilian open innovation The results show that the commitments made by the Brazilian government are compatible with the public open innovation process. The actions in the Plan are related specifically to transparency, open data and preparation of the governance body for the open innovation process